Related MeSH Hierarchy (4)
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Alkaloids » Opiate Alkaloids » Morphinans » Buprenorphine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Bridged-Ring » Morphinans » Buprenorphine
Chemicals and Drugs [D] » Heterocyclic Compounds [D03] » Heterocyclic Compounds, Fused-Ring » Heterocyclic Compounds, 4 or More Rings » Morphinans » Buprenorphine
Chemicals and Drugs [D] » Polycyclic Compounds [D04] » Polycyclic Aromatic Hydrocarbons » Phenanthrenes » Morphinans » Buprenorphine
Description
A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use. MeSH
Hierarchy View
Subtype Terms (1)
Phase 2 Indicated Drugs (3)
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