Adie Syndrome D000270

Related MeSH Hierarchy (4)

Diseases [C] » Eye Diseases [C11] » Pupil Disorders » Tonic Pupil » Adie Syndrome

Diseases [C] » Nervous System Diseases [C10] » Autonomic Nervous System Diseases » Adie Syndrome

Diseases [C] » Eye Diseases [C11] » Ocular Motility Disorders » Oculomotor Nerve Diseases » Adie Syndrome

Description

A syndrome characterized by a TONIC PUPIL that occurs in combination with decreased lower extremity reflexes. The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction. Pathologic features include degeneration of the ciliary ganglion and postganglionic parasympathetic fibers that innervate the pupillary constrictor muscle. (From Adams et al., Principles of Neurology, 6th ed, p279)   MeSH

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