Active Ingredient History

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Sucralose is an artificial sweetener and sugar substitute. As the majority of ingested sucralose is not metabolized by the body, it adds no calories. In the European Union, it is also known under the E number E955. It is produced by chlorination of sucrose, selectively replacing three of the hydroxy groups—in the C1 and C6 positions of the fructose portion and the C4 position of the glucose portion—to give a 1,6-dichloro-1,6-dideoxyfructose–4-chloro-4-deoxygalactose disaccharide. Sucralose is about 600 times sweeter than sucrose, three times as sweet as both aspartame and acesulfame potassium, and twice as sweet as sodium saccharin.   Wikipedia

  • SMILES: OC[C@@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H](O)[C@H]1Cl
  • InChIKey: BAQAVOSOZGMPRM-KBFHZYTNSA-N
  • Mol. Mass: 397.64
  • ALogP: -1.66
  • ChEMBL Molecule:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No
1',4',6'-trichloro-1',4,6'-trideoxygalactosucrose | 1,6-dichloro-1,6-dideoxy-beta-d-fructofuranosyl-4-chloro-4-deoxy-alpha-d-galactopyranoside | alpha-d-galactopyranoside, 1,6-dichloro-1,6-dideoxy-beta-d-fructofuranosyl 4-chloro-4-deoxy- | splenda | sucralose | trichlorogalactosucrose | trichlorogalacto-sucrose | trichlorosucrose

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