125-iodine Report issue

Small molecule Experimental
AACT DrugBank PubChem

Active Ingredient History

NOW
  • Now
Iodide ion I-125 is radioisotope of iodine with half-life 59.4 days. It decays with the emission of low-energy gamma rays. It is used as a source for bone densitometry devices, protein iodination. Seeds implantations with I-125 are used in the clinics for the treatment of prostate cancer, malignant biliary obstruction, non-small cell lung cancer, colorectal cancer, uveal melanoma, and other tumors.   NCATS

Chemistry

  • SMILES: [125I-]
  • InChIKey: XMBWDFGMSWQBCA-YPZZEJLDSA-M
  • Mol. Mass: 124.90462415
  • ALogP: Missing data
  • ChEMBL Molecules: Missing data
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Missing data
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: Missing data

Alternative names

125-iodine | 131i | i131 | i-131 | iodide-131 | iodide i-131 | iodide i-131 ion | iodide ion i 131 | iodide ion, i-131 | iodine-125 | iodine 131 | iodine-131 | iodine i 125 | iodine i 131 | iodine i-131 | radioiodine

Organizations (43)

Research & Development (43)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (15)

Approved Indications (1)


 

Neoplasms

Experimental Indications - Clinical Trial Phases 1-4 (14)


 

Brain Neoplasms (Phase 2)

Exophthalmos (Phase 3)

Graves Disease (Phase 3)

Head and Neck Neoplasms (Phase 1)

Hypothyroidism (Phase 3)

Lung Neoplasms (Phase 3)

Lymphoma, AIDS-Related (Phase 2)

Lymphoma, Large-Cell, Anaplastic (Phase 2)

Lymphoma, Non-Hodgkin (Phase 2)

Neuroblastoma (Phase 3)

Prostatic Neoplasms (Phase 3)

Retinoblastoma (Phase 3)

Sarcoma (Phase 2)

Thyroid Neoplasms (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 35
  • # of Trial Organizations: 43

Trials by Phase

Trial Phase Start Date Organizations Indications

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