Active Ingredient History
Bifidobacterium longum is a Gram-positive, catalase-negative, rod-shaped bacterium present in the human gastrointestinal tract and one of the 32 species that belong to the genus Bifidobacterium. It is a microaerotolerant anaerobe and considered to be one of the earliest colonizers of the gastrointestinal tract of infants. When grown on general anaerobic medium, B. longum forms white, glossy colonies with a convex shape. B. longum is one of the most common bifidobacteria present in the gastrointestinal tracts of both children and adults. B. longum is non-pathogenic, is often added to food products, and its production of lactic acid is believed to prevent growth of pathogenic organisms. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Abdominal Pain (Phase 3)
Acute-On-Chronic Liver Failure (Phase 2/Phase 3)
Adenomatous Polyposis Coli (Phase 2)
Aged (Early Phase 1)
Amoxicillin (Phase 4)
Anxiety (Phase 4)
Ascites (Phase 2)
Asthma (Phase 1/Phase 2)
Breast Neoplasms (Phase 2/Phase 3)
Carcinoma, Non-Small-Cell Lung (Phase 2)
Celiac Disease (Phase 4)
Child Development (Phase 3)
Clostridioides difficile (Phase 3)
Cognitive Dysfunction (Phase 4)
Colic (Phase 4)
Colonoscopy (Phase 4)
Constipation (Phase 4)
Crohn Disease (Phase 4)
Deglutition Disorders (Early Phase 1)
Depression (Phase 3)
Depressive Disorder (Phase 3)
Depressive Disorder, Major (Phase 3)
Dermatology (Phase 3)
Diabetes Mellitus, Type 2 (Phase 2/Phase 3)
Diarrhea (Phase 3)
Diverticulitis (Phase 2)
Drug Resistance, Bacterial (Phase 2)
Dysbiosis (Phase 4)
Dyspepsia (Phase 1/Phase 2)
Esophageal and Gastric Varices (Phase 3)
Fatty Liver (Phase 1)
Fever (Phase 3)
Fibrosis (Phase 4)
Gastrointestinal Diseases (Phase 4)
Gastrointestinal Microbiome (Phase 3)
General Surgery (Phase 3)
Glutens (Phase 2)
Growth (Phase 3)
Healthy Volunteers (Phase 2/Phase 3)
Hepatic Encephalopathy (Phase 4)
Hirschsprung Disease (Phase 2)
Hypersensitivity (Phase 4)
Immune System Diseases (Phase 3)
Inflammatory Bowel Diseases (Phase 3)
Intestinal Neoplasms (Phase 3)
Irritable Bowel Syndrome (Phase 4)
Klebsiella pneumoniae (Phase 1/Phase 2)
Live Birth (Phase 2)
Liver Cirrhosis (Phase 2/Phase 3)
Metabolic Syndrome (Phase 3)
Neoplasms (Phase 3)
Non-alcoholic Fatty Liver Disease (Phase 3)
Obsessive-Compulsive Disorder (Phase 4)
Osteoporosis (Phase 2)
Peritonitis (Phase 2/Phase 3)
Pneumonia (Phase 3)
Postoperative Complications (Phase 4)
Prebiotics (Phase 1)
Prediabetic State (Phase 2/Phase 3)
Probiotics (Phase 4)
Psychological Distress (Phase 3)
Quality of Life (Phase 3)
Quorum Sensing (Phase 1)
Scleroderma, Systemic (Phase 2)
Sepsis (Phase 1)
Signs and Symptoms, Digestive (Phase 1/Phase 2)
Sleep Disorders, Intrinsic (Phase 2)
Stress, Psychological (Phase 3)
Tooth Extraction (Phase 4)
Water Loss, Insensible (Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
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