Active Ingredient History
Silver Dihydrogen Citrate is a patented antimicrobial based on stabilized silver ion complex produced by a unique electrochemical process with silver and citric acid. Silver Dihydrogen Citrate provides a broad spectrum antimicrobial activity and is effective against unwanted bacteria, fungi, and viruses including pathogenic microorganisms. Its fast killing activity makes Silver Dihydrogen Citrate an effective antimicrobial for many applications. Silver has been used for centuries for its antimicrobial properties. In order for silver to be effective in killing microorganisms, it must be in an ionic form. Silver Dihydrogen Citrate is a complex of one silver ion weakly bound to one citrate ion having the molecular complex AgC6H7O7. Silver Dihydrogen Citrate provides a stabilized form of silver ion in an organic acid (citric acid). The bioavailability of the ions allows for Silver Dihydrogen Citrate to be rapidly effective against a broad spectrum of bacteria, viruses, and fungi. Silver ions are highly attracted to sulfur-containing thiol groups found in metabolic and structural proteins bound to the membrane surface. Silver Dihydrogen Citrate targets these critical proteins and destroys their structure. This disruption of the organisms’ membrane function and integrity lyses the membrane and the organism dies. NCATS
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Cariostatic Agents (Phase 4)
Dental Caries (Phase 4)
Dental Caries Susceptibility (Phase 4)
Dentin Sensitivity (Phase 2/Phase 3)
Fluorides, Topical (Phase 4)
Gastrointestinal Microbiome (Phase 3)
Infections ()
Inflammation ()
Tinea ()
Tooth, Deciduous (Phase 3)
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