Active Ingredient History
Superoxide dismutase 2, mitochondrial (SOD2), also known as manganese-dependent superoxide dismutase (MnSOD), is an enzyme which in humans is encoded by the SOD2 gene on chromosome 6. A related pseudogene has been identified on chromosome 1. Alternative splicing of this gene results in multiple transcript variants. This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Diabetes Mellitus (Phase 2)
Drug-Related Side Effects and Adverse Reactions (Phase 1/Phase 2)
Esophageal Diseases (Phase 1/Phase 2)
Frail Elderly (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 2)
Renal Dialysis (Phase 4)
Skin Care ()
Sleep Apnea Syndromes (Early Phase 1)
Vaccines (Phase 4)
Virus Diseases (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
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