API | cedazuridine

cedazuridine (Inqovi) Report issue

Small molecule Orphan Drug ^FDA Approved ^FDA Priority Review ^FDA

AACT

Active Ingredient History

NOW

Now

Chemistry

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More Chemistry

Pharmacology

Mechanism of Action:
- Cytidine deaminase (Mus musculus) ^UniProt
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Combination drugs

inqovi ( decitabine (dacogen), cedazuridine (Inqovi) - other name: decitabine and cedazuridine )

astx727

Organizations (34)

Research & Development (34)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (24)

Approved Indications (1)

Myelodysplastic Syndromes (approved 2020)

Experimental Indications - Clinical Trial Phases 1-4 (24)

BRCA1 Protein (Phase 1)

Breast Neoplasms (Phase 1)

Fusion Proteins, bcr-abl (Phase 2)

Healthy Volunteers (Phase 1)

Hodgkin Disease (Phase 1)

Leukemia (Phase 2)

Leukemia, Myelogenous, Chronic, BCR-ABL Positive (Phase 2/Phase 3)

Leukemia, Myeloid, Acute (Phase 3)

Leukemia, Myeloid, Chronic-Phase (Phase 2)

Leukemia, Myelomonocytic, Chronic (Phase 3)

Lymphoma, Large B-Cell, Diffuse (Phase 1)

Lymphoma, Non-Hodgkin (Phase 1)

Lymphoma, T-Cell (Phase 1/Phase 2)

Melanoma (Phase 1/Phase 2)

Mesothelioma (Phase 2)

Mutation (Phase 1)

Myelodysplastic Syndromes (Phase 3)

Myeloproliferative Disorders (Phase 2)

Neoplasms (Phase 1)

Nerve Sheath Neoplasms (Phase 2)

Neuroendocrine Tumors (Phase 1)

Patient Preference (Phase 3)

Prostatic Neoplasms, Castration-Resistant (Phase 1)

Triple Negative Breast Neoplasms (Phase 1)

Overview

Highest Phase: Phase 3
# of Trials: 50
# of Trial Organizations: 34

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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