l-isoleucine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Isoleucine is an essential α-amino acid that is used in the biosynthesis of proteins. L-isoleucine is commonly used in parenteral and enteral nutrition. It is used in combination with the other branched chain amino acids to improve the nutritional status of patients with hepatic diseases. BCAAs serve as important fuel sources for skeletal muscle during periods of metabolic stress   NCATS

Chemistry

  • SMILES: CC[C@H](C)[C@H](N)C(O)=O
  • InChIKey: AGPKZVBTJJNPAG-WHFBIAKZSA-N
  • Mol. Mass: 131.1729
  • ALogP: 0.44
  • ChEMBL Molecule:
    isoleucine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

2-amino-3-methylvaleric acid | (2s,3s)-2-amino-3-methylpentanoic acid | alpha-amino-beta-methylvaleric acid | i | ile | isoleucine | l-isoleucine | α-amino-β-methylvaleric acid

Organizations (6)

Research & Development (6)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (5)

Approved Indications (1)


 

Burns (approved 1971)

Experimental Indications - Clinical Trial Phases 1-4 (4)


 

Diarrhea (Phase 2)

Dietary Supplements ()

Hyperglycemia ()

Liver Cirrhosis (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 5
  • # of Trial Organizations: 6

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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