Active Ingredient History
Tamsulosin, a sulfamoylphenethylamine-derivative alpha-adrenoceptor blocker with enhanced specificity for the alpha-adrenoceptors of the prostate, is commonly used to treat benign prostatic hyperplasia (BPH). The drug is commercially available in a racemic mixture of 2 isomers, and is pharmacologically related to doxazocin, prazosin, and terazosin. However, unlike these drugs, tamsulosin has a higher affinity for the alpha-1A- adrenergic receptors, which are located in vascular smooth muscle. Studies show that tamsulosin has about 12 times greater affinity for alpha-1 adrenergic receptors in the prostate than those in the aorta, which may result in a reduced incidence of adverse cardiovascular effects. Tamsulosin is sold under the trade name Flomax. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Combination drugs
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Anesthesia, Epidural (Phase 3)
Arthropathy, Neurogenic (Phase 4)
Cardiovascular Diseases (Phase 1)
Choroid Diseases (Phase 4)
Colorectal Surgery (Phase 3)
Depressive Disorder (Phase 1)
Drug Interactions (Phase 1)
Drugs, Investigational (Phase 1)
Erectile Dysfunction (Phase 3)
General Surgery (Phase 4)
Healthy Volunteers (Phase 1)
Heart Diseases (Phase 4)
Hernia (Phase 4)
Hernia, Inguinal (Phase 4)
Hyperplasia (Phase 3)
Hypertension (Phase 1)
Kidney Calculi (Phase 3)
Kidney Diseases (Phase 4)
Lower Urinary Tract Symptoms (Phase 4)
Macular Edema (Phase 1/Phase 2)
Neoplasms (Phase 3)
Nephrolithiasis (Phase 4)
Nocturia (Phase 4)
Pain (Phase 4)
Pelvic Organ Prolapse (Phase 2/Phase 3)
Pharmacokinetics (Phase 1)
Postoperative Complications (Phase 4)
Premature Ejaculation (Phase 3)
Prostatic Neoplasms (Phase 4)
Prostatitis (Phase 4)
Pupil Disorders (Phase 4)
Quality of Life (Phase 4)
Rectal Neoplasms (Phase 3)
Renal Colic (Phase 4)
Stents (Phase 3)
Tamsulosin (Phase 3)
Thoracic Diseases (Phase 4)
Thoracic Surgery (Phase 3)
Ureteral Calculi (Phase 4)
Ureteral Diseases (Phase 4)
Ureteral Obstruction (Phase 4)
Ureterolithiasis (Phase 4)
Urinary Bladder Neck Obstruction (Phase 2)
Urinary Bladder Neoplasms (Phase 4)
Urinary Bladder, Neurogenic (Phase 2/Phase 3)
Urinary Bladder, Overactive (Phase 4)
Urinary Calculi (Phase 4)
Urinary Catheterization (Phase 3)
Urinary Incontinence (Phase 4)
Urinary Incontinence, Stress (Phase 2/Phase 3)
Urinary Retention (Phase 4)
Urinary Tract Infections (Phase 4)
Urinary Tract Physiological Phenomena (Phase 4)
Urination Disorders (Phase 4)
Urolithiasis (Phase 4)
Urological Manifestations (Phase 3)
Urologic Diseases (Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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