Active Ingredient History
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Celecoxib is an analgesic that is FDA approved for the treatment of osteoarthritis，rheumatoid arthritis，juvenile rheumatoid arthritis, ankylosing, spondylitis, acute pain and primary dysmenorrhea. The mechanism of action of Celecoxib is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2). Concomitant use of Celecoxib and analgesic doses of aspirin is not generally recommended. Concomitant use with Celecoxib may diminish the antihypertensive effect of ACE Inhibitors, Angiotensin Receptor Blockers (ARB), or BetaBlockers and can increase serum concentration and prolong half-life of digoxin. Common adverse reactions include hypertension, diarrhea, nausea and headache. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Combination drugs
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Acute Febrile Encephalopathy (Phase 2)
Acute Pain (Phase 3)
alpha-Mannosidosis (Phase 2)
Alzheimer Disease (Phase 3)
Amyotrophic Lateral Sclerosis (Phase 2)
Analgesia (Phase 3)
Analgesics (Phase 4)
Analgesics, Opioid (Phase 4)
Anemia (Phase 1)
Angioplasty, Balloon, Coronary (Phase 4)
Ankle Injuries (Phase 4)
Anterior Cruciate Ligament Injuries (Phase 3)
Arthritis (Phase 4)
Arthritis, Gouty (Phase 3)
Arthropathy, Neurogenic (Phase 4)
Arthroplasty (Phase 2/Phase 3)
Arthroplasty, Replacement, Knee (Phase 4)
Arthroscopy (Phase 4)
Aspartylglucosaminuria (Phase 2)
Axial Spondyloarthritis (Phase 4)
Back Pain (Phase 4)
Bile Duct Neoplasms (Phase 4)
Bipolar Disorder (Phase 4)
Body Fat Distribution (Phase 1/Phase 2)
Bone and Bones (Phase 1)
Bone Resorption (Phase 1)
Brain Diseases (Phase 1)
Brain Neoplasms (Phase 2)
Breast Neoplasms (Phase 3)
Carcinoma (Phase 2)
Carcinoma, Hepatocellular (Phase 4)
Carcinoma, Mucoepidermoid (Phase 2)
Carcinoma, Non-Small-Cell Lung (Phase 3)
Carcinoma, Renal Cell (Phase 2)
Cardiovascular Diseases (Phase 4)
Celecoxib (Phase 3)
Central Serous Chorioretinopathy (Phase 1)
Cerebral Hemorrhage (Phase 2)
Cerebrovascular Disorders (Phase 3)
Cholecystectomy, Laparoscopic (Phase 3)
Chronic Pain (Phase 3)
Colonic Neoplasms (Phase 4)
Colorectal Neoplasms (Phase 4)
Colposcopy (Phase 4)
Constipation (Phase 4)
Coronary Artery Disease (Phase 4)
Coronary Restenosis (Phase 4)
COVID-19 (Phase 2)
Crohn Disease (Phase 4)
Cyclooxygenase 2 Inhibitors (Phase 4)
Deficiency Diseases (Phase 2)
Depression (Phase 3)
Depression, Postpartum (Phase 3)
Depressive Disorder, Major (Phase 4)
Diabetes Mellitus, Type 2 (Phase 1/Phase 2)
Diabetic Retinopathy (Phase 4)
Diarrhea (Phase 1)
DNA Mismatch Repair (Phase 2)
Drug Interactions (Phase 1)
Drugs, Investigational (Phase 3)
Drug Therapy (Phase 2)
Duodenal Neoplasms (Phase 2/Phase 3)
Edema (Phase 1)
Endometrial Neoplasms (Phase 2)
Ependymoma (Phase 2)
Epiretinal Membrane (Phase 1)
Esophageal Neoplasms (Phase 2)
Facial Pain (Phase 2)
Fallopian Tube Neoplasms (Phase 2)
Food-Drug Interactions (Phase 2)
Fractures, Stress (Phase 1)
Fucosidosis (Phase 2)
General Surgery (Phase 4)
Genetic Diseases, Inborn (Phase 2)
Glioblastoma (Phase 2)
Glioma (Phase 2)
Graves Ophthalmopathy (Phase 2)
Growth and Development (Early Phase 1)
Hamartoma (Phase 2)
Hand Injuries (Phase 3)
Head and Neck Neoplasms (Phase 3)
Healthy Volunteers (Phase 4)
Heart (Phase 1)
Hemorrhage ()
Hepatitis B (Phase 2)
Hepatolenticular Degeneration (Phase 1)
HLA-A2 Antigen (Phase 2)
Hodgkin Disease (Phase 1)
Hyperalgesia (Phase 2)
Hyperlipidemias (Phase 4)
Hypertension (Phase 4)
Hypopharyngeal Neoplasms (Phase 2)
Hypotension, Orthostatic (Phase 1)
Hysteroscopy (Phase 3)
Inflammation (Phase 4)
Inflammatory Bowel Diseases (Phase 4)
Influenza, Human (Phase 3)
Intestinal Polyposis (Phase 4)
Intestinal Polyps (Phase 2/Phase 3)
Keratosis, Actinic (Phase 2/Phase 3)
Laryngeal Neoplasms (Phase 2)
Leiomyoma (Phase 4)
Leukemia (Phase 2)
Leukemia, Lymphocytic, Chronic, B-Cell (Phase 1)
Leukemia, Myeloid, Acute (Phase 1)
Leukemia, Myeloid, Chronic-Phase (Phase 1)
Leukemia, Myelomonocytic, Chronic (Phase 1)
Leukodystrophy, Globoid Cell (Phase 2)
Leukodystrophy, Metachromatic (Phase 2)
Ligaments (Phase 4)
Liver Neoplasms (Phase 3)
Low Back Pain (Phase 4)
Lung Diseases (Phase 4)
Lung Neoplasms (Phase 3)
Lymphangioleiomyomatosis (Phase 2)
Lymphoma (Phase 2)
Lymphoma, Non-Hodgkin (Phase 1)
Macular Degeneration (Phase 3)
Magnetic Resonance Imaging (Phase 4)
Medulloblastoma (Phase 2)
Melanoma (Phase 2)
Memory Disorders (Phase 3)
Meniscus (Early Phase 1)
Mesothelioma (Phase 1/Phase 2)
Mesothelioma, Malignant (Phase 3)
Metabolic Diseases (Phase 2)
Microsatellite Instability (Phase 1)
Migraine Disorders (Phase 3)
Migraine with Aura (Phase 2)
Migraine without Aura (Phase 2)
Mood Disorders (Phase 3)
Mouth Neoplasms (Phase 2/Phase 3)
Mucopolysaccharidoses (Phase 2)
Mucopolysaccharidosis I (Phase 2)
Mucopolysaccharidosis II (Phase 2)
Mucopolysaccharidosis VI (Phase 2)
Mucopolysaccharidosis VII (Phase 2)
Multiple Myeloma (Phase 2)
Musculoskeletal Pain (Phase 1)
Mutation (Phase 2)
Myelodysplastic Syndromes (Phase 1)
Myeloproliferative Disorders (Phase 1)
Myocardial Ischemia (Phase 4)
Myositis (Phase 1)
Narcotics (Phase 4)
Nasopharyngeal Carcinoma (Phase 3)
Nausea (Phase 4)
Neoadjuvant Therapy (Phase 1)
Neoplasm Metastasis (Phase 2)
Neoplasms ()
Neoplasms, Germ Cell and Embryonal (Phase 1)
Neuralgia (Phase 2)
Neuroblastoma (Phase 2)
Neurofibromatosis 1 (Phase 2)
Neuroinflammatory Diseases (Phase 4)
Obesity (Phase 1/Phase 2)
Obsessive-Compulsive Disorder (Phase 2)
Oropharyngeal Neoplasms (Phase 2)
Osteoarthritis, Hip (Phase 4)
Osteoarthritis, Knee (Phase 4)
Osteopetrosis (Phase 2)
Ovarian Neoplasms (Phase 2)
Pain ()
Pain Management (Phase 4)
Pain, Postoperative (Phase 4)
Pancreatic Neoplasms (Phase 4)
Paranasal Sinus Neoplasms (Phase 1/Phase 2)
Paresthesia (Phase 3)
Peptic Ulcer (Phase 4)
Peritoneal Neoplasms (Phase 1/Phase 2)
Peroxisomal Disorders (Phase 2)
Pharmacokinetics (Phase 4)
Pharyngeal Neoplasms (Phase 1/Phase 2)
Pharyngitis (Phase 3)
Photochemotherapy (Phase 1)
Precancerous Conditions (Phase 2/Phase 3)
Pre-Eclampsia (Phase 2)
Pregabalin (Phase 2/Phase 3)
Primary Myelofibrosis (Phase 1)
Prostatic Hyperplasia (Phase 4)
Prostatic Neoplasms (Phase 2/Phase 3)
Prostatitis (Phase 4)
Psychiatry (Phase 2)
Pure Autonomic Failure (Phase 1)
Rectal Neoplasms (Phase 3)
Refsum Disease, Infantile (Phase 2)
Retinal Diseases (Phase 1)
Retinal Vein Occlusion (Phase 1)
Rhabdoid Tumor (Phase 2)
Rotator Cuff Injuries (Phase 4)
Sarcoma (Phase 2)
Schizophrenia (Phase 4)
Shoulder Injuries (Phase 4)
Shoulder Pain (Phase 4)
Sinusitis (Phase 4)
Sleep Apnea, Obstructive (Phase 1/Phase 2)
Small Cell Lung Carcinoma (Phase 1)
Smoking (Phase 3)
Smoldering Multiple Myeloma (Phase 2)
Sphingolipidoses (Phase 2)
Sphingomyelins (Phase 2)
Spinal Diseases (Phase 3)
Spinal Stenosis (Phase 4)
Spondylarthropathies (Phase 4)
Squamous Cell Carcinoma of Head and Neck (Phase 2)
Squamous Intraepithelial Lesions (Phase 2)
Stomach Neoplasms (Phase 2)
Stomach Ulcer (Phase 3)
Stomatitis (Phase 2)
Stroke (Phase 1/Phase 2)
Survival (Phase 2)
Temporomandibular Joint Disorders (Phase 2)
Thoracic Neoplasms (Phase 1/Phase 2)
Thymoma (Phase 1)
Thyroidectomy (Phase 4)
Tobacco Use Disorder (Phase 1/Phase 2)
Tongue Neoplasms (Phase 2)
Tonsillectomy (Phase 2)
Tonsillitis (Phase 2)
Tuberculosis (Phase 1)
Ureteral Calculi (Phase 4)
Urethral Stricture (Phase 4)
Urinary Bladder Neoplasms (Phase 2/Phase 3)
Uterine Artery Embolization (Phase 4)
Uterine Cervical Neoplasms (Phase 2)
Uterine Neoplasms (Phase 2)
Vascular Diseases (Phase 4)
Venous Cutdown (Phase 4)
Vitreous Body (Phase 1)
Zellweger Syndrome (Phase 2)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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