Active Ingredient History

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Brimonidine reduces the amount of fluid in the eye, which decreases pressure inside the eye. Brimonidine ophthalmic (for the eyes) is used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye). Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). Fluorophotometric studies in animals and humans suggest that Brimonidine has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow. Adverse reactions occurring in approximately 10­20% of the subjects receiving brimonidine ophthalmic solution (0.1-0.2%) included: allergic conjunctivitis, conjunctival hyperemia, and eye pruritus. Because Brimonidine may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with Brimonidine is advised.   NCATS

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Drug Pricing (per unit)

United States

$0.1353 - $36.1206

Australia

$9.2493 - $10.3503
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

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( brimonidine (alphagan), brinzolamide (azopt) - other name: simbrinza 0.2%/1% ophthalmic suspension )
5-bromo-6-(2-imidazolin-2-ylamino)quinoxaline | agn-190342-lf | alphagan | brimonidina | brimonidine | brimonidine l-tartarate | brimonidine tartrate | brimonidinum | brinzolamide / brimonidine tartrate | bromoxidine | brymont | mirvaso | uk 14,304 | uk-14304 | uk-1430418

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