Active Ingredient History
Bifidobacterium longum is a Gram-positive, catalase-negative, rod-shaped bacterium present in the human gastrointestinal tract and one of the 32 species that belong to the genus Bifidobacterium. It is a microaerotolerant anaerobe and considered to be one of the earliest colonizers of the gastrointestinal tract of infants. When grown on general anaerobic medium, B. longum forms white, glossy colonies with a convex shape. While B. longum is not significantly present in the adult gastrointestinal tract, it is considered part of the gut microbiota and its production of lactic acid is believed to prevent growth of pathogenic organisms. B. longum is non-pathogenic and is often added to food products. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Abdominal Pain (Phase 2/Phase 3)
Acute-On-Chronic Liver Failure (Phase 3)
Adenomatous Polyposis Coli (Phase 2)
Aged (Early Phase 1)
Ascites (Phase 2)
Asthma (Phase 1/Phase 2)
Bipolar Disorder (Phase 2)
Celiac Disease (Phase 4)
Cognitive Dysfunction (Phase 4)
Colic (Phase 4)
Colitis, Ulcerative (Phase 2/Phase 3)
Crohn Disease (Phase 4)
Deglutition Disorders (Early Phase 1)
Dermatitis, Atopic (Phase 1)
Diabetes Mellitus (Phase 2)
Diarrhea (Phase 3)
Drug Resistance, Bacterial (Phase 2)
Esophageal and Gastric Varices (Phase 3)
Fatty Liver (Phase 2)
Fibrosis (Phase 4)
Food Hypersensitivity (Phase 1)
Gastroenteritis (Phase 3)
Gastrointestinal Microbiome (Phase 3)
General Surgery (Phase 3)
Healthy Volunteers (Phase 1)
Hepatic Encephalopathy (Phase 4)
Hirschsprung Disease (Phase 2)
Hyperoxaluria (Phase 1/Phase 2)
Hypersensitivity (Phase 4)
Infant, Low Birth Weight (Phase 2/Phase 3)
Inflammation (Phase 2)
Inflammatory Bowel Diseases (Phase 3)
Intestinal Neoplasms (Phase 3)
Irritable Bowel Syndrome (Phase 4)
Kidney Failure, Chronic (Phase 2)
Klebsiella pneumoniae (Phase 1/Phase 2)
Liver Cirrhosis (Phase 2/Phase 3)
Neonatal Sepsis (Phase 3)
Nephrolithiasis (Phase 1/Phase 2)
Non-alcoholic Fatty Liver Disease (Phase 1/Phase 2)
Osteoporosis (Phase 2)
Peritonitis (Phase 3)
Probiotics (Phase 4)
Psoriasis (Phase 1/Phase 2)
Scleroderma, Systemic (Phase 2)
Severe Acute Malnutrition (Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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