crizotinib (xalkori) Report issue

Small molecule Orphan Drug FDA Approved FDA First in Class Accelerated Approval FDA Priority Review FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem

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Chemistry

Mol. Mass

450.337

ALogP

5.04

Rule of 5

No

Rule of 3

No
Details
  • SMILES: C[C@@H](OC1=CC(=CN=C1N)C2=CN(N=C2)C3CCNCC3)C4=C(Cl)C=CC(F)=C4Cl
  • InChIKey: KTEIFNKAUNYNJU-GFCCVEGCSA-N
    1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1
  • Chirality: Single Stereoisomer
  • Inorganic: No
  • Polymer: No

Sources

CHEMBL601719   ChEMBL
crizotinib

53AH36668S   NCATS
crizotinib *

Crizotinib   Wikipedia

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