Active Ingredient History

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Coumarin itself was first isolated from the tonka bean Coumarouna odorata. Coumarin and its derivatives are alpha-benzopyrones. Coumarin is metabolized in humans to 7-hydroxycoumarin. Coumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties. For the carcinogenic effect, a genotoxic mechanism was considered possible. Coumarins have a significant effect on physiological, bacteriostatic and anti-tumor activity. Coumarins have potent edema protective function and thus involved in the treatment of lymphedema, elephantiasis and other high protein edema conditions. Coumarin has appetite-suppressing properties.   NCATS

  • SMILES: O=C1OC2=C(C=CC=C2)C=C1
  • InChIKey: ZYGHJZDHTFUPRJ-UHFFFAOYSA-N
  • Mol. Mass: 146.1427
  • ALogP: 1.45
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No
1,2-benzopyrone | 2-chromenone | 2h-1-benzopyran-2-one | 2h-benzo(b)pyran-2-one | 5,6-benzo-alpha-pyrone | coumarin | coumarinic lactone | cumarin | dipteryx | lodema

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