tezacaftor (Trifakta) Report issue

Small molecule Orphan Drug FDA Approved FDA Fast Track FDA Priority Review FDA
AACT ChEMBL DrugBank PubChem

Back

Chemistry

Mol. Mass

520.4976

ALogP

3.4

Rule of 5

No

Rule of 3

No
Details
  • SMILES: CC(C)(CO)C1=CC2=CC(NC(=O)C3(CC3)C4=CC=C5OC(F)(F)OC5=C4)=C(F)C=C2N1C[C@@H](O)CO
  • InChIKey: MJUVRTYWUMPBTR-MRXNPFEDSA-N
    1S/C26H27F3N2O6/c1-24(2,13-33)22-8-14-7-18(17(27)10-19(14)31(22)11-16(34)12-32)30-23(35)25(5-6-25)15-3-4-20-21(9-15)37-26(28,29)36-20/h3-4,7-10,16,32-34H,5-6,11-13H2,1-2H3,(H,30,35)/t16-/m1/s1
  • Chirality: Single Stereoisomer
  • Inorganic: No
  • Polymer: No

Sources

CHEMBL3544914   ChEMBL
tezacaftor

8RW88Y506K   NCATS
tezacaftor *

Tezacaftor   Wikipedia

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue