tetrodotoxin Report issue

Small molecule Experimental
AACT DrugBank PubChem

Active Ingredient History

NOW
  • Now
Tetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Although tetrodotoxin was discovered in these fish, it is found in several other animals. It is also produced by certain infectious or symbiotic bacteria like Pseudoalteromonas, Pseudomonas, and Vibrio as well as other species found in symbiotic relationships with animals and plants.   Wikipedia

Chemistry

  • SMILES: NC1=N[C@H](O)[C@H]2[C@H]3O[C@]4(O)O[C@@H]([C@@H](O)[C@@]2(N1)[C@@H]4O)[C@]3(O)CO
  • InChIKey: CFMYXEVWODSLAX-QOZOJKKESA-N
  • Mol. Mass: 319.27
  • ALogP: -5.52
  • ChEMBL Molecule:
    tetrodotoxin  
More Chemistry

Pharmacology

Alternative names

tetrodotoxin

Organizations (3)

Research & Development (3)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (7)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (7)


 

Cardiotoxicity (Phase 1)

Drug-Related Side Effects and Adverse Reactions (Phase 2)

Healthy Volunteers (Phase 1)

Neoplasms (Phase 3)

Neuralgia (Phase 2)

Pain (Phase 3)

Peripheral Nervous System Diseases (Phase 2)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 6
  • # of Trial Organizations: 3

Trials by Phase

Trial Phase Start Date Organizations Indications

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