Active Ingredient History

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Tedizolid phosphate is an oxazolidinone prodrug which in the body is dephosphorylated to the active compound tedizolid. The antibacterial activity of tedizolid is mediated by binding to the 50S subunit of the bacterial ribosome resulting in inhibition of protein synthesis. Tedizolid inhibits bacterial protein synthesis through a mechanism of action different from that of other non-oxazolidinone class antibacterial drugs; therefore, cross-resistance between tedizolid and other classes of antibacterial drugs is unlikely. Tedizolid is bacteriostatic against Gram Positive bacteria such as enterococci, staphylococci, and streptococci. No drug-drug interactions were identified with tedizolid.   NCATS

  • SMILES: CN1N=NC(=N1)C2=NC=C(C=C2)C3=CC=C(C=C3F)N4C[C@H](CO)OC4=O
  • InChIKey: XFALPSLJIHVRKE-GFCCVEGCSA-N
  • Mol. Mass: 370.3378
  • ALogP: 1.4
  • ChEMBL Molecules:
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Drug Pricing (per unit)

United States

$277.8227 - $2294.2200
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

3-(3-fluoro-4-(6-(2-methyl-2h-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one | 3-(3-fluoro-4-(6-(2-methyl-2h-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-hydroxymethyloxazolidin-2-one | [(5r)-3-{3-fluoro-4-[6-(2-methyl-2h-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate | da7218 | da 7218 | da-7218 | sivextro | tedizolid | tedizolid phosphate | torezolid | torezolid phosphate | tr 700 | tr-700 | tr701 | tr 701 | tr-701 | tr701 cpd | tr-701-fa

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