API | sodium stibogluconate

sodium stibogluconate (Pentostam) Report issue

Small molecule Experimental

AACT ChEMBL DrugBank Drug Central PubChem repoDB

Active Ingredient History

NOW

Sodium stibogluconate, sold under the brand name Pentostam among others, is a medication used to treat leishmaniasis. This includes leishmaniasis of the cutaneous, visceral, and mucosal types. Some combination of miltefosine, paramycin and liposomal amphotericin B, however, may be recommended due to issues with resistance. It is given by injection. ^Wikipedia

Chemistry

SMILES: Missing data
InChIKey: Missing data
Mol. Mass: Missing data
ALogP: Missing data
ChEMBL Molecule:
sodium stibogluconate

More Chemistry

Pharmacology

Mechanism of Action:
- DNA topoisomerase type IB small subunit (Leishmania major) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

estibogluconato sodico | myostibin | natrii stibogluconas | pentostam | sodium stibogluconate | solusurmin | stibanate | stibanose | stibatin | stibinol | stibogluconate de sodium | stibogluconate sodium | trisodium 1-{[3-carboxylato-5-(1,2-dihydroxyethyl)-1-hydroxy-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]hept-1-yl]oxy}-5-(1,2-dihydroxyethyl)-1-oxido-2,6,7-trioxa-1lambda(5)-stibabicyclo[2.2.1]heptane-3-carboxylate nonahydrate

Organizations (31)

Research & Development (31)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (10)

Approved Indications (1)

Leishmaniasis

Experimental Indications - Clinical Trial Phases 1-4 (10)

Antimony Sodium Gluconate (Phase 2)

Leishmaniasis (Phase 2)

Leishmaniasis, Cutaneous (Phase 4)

Leishmaniasis, Visceral (Phase 3)

Leukemia, Myeloid, Acute (Phase 2)

Melanoma (Phase 1)

Mutation (Phase 2)

Myelodysplastic Syndromes (Phase 2)

Neoplasms (Phase 2)

Wound Healing (Phase 2)

Overview

Highest Phase: Phase 4
# of Trials: 19
# of Trial Organizations: 31

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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