API | navarixin

navarixin Report issue

Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW

Chemistry

SMILES: CC[C@@H](NC1=C(Nc2cccc(C(=O)N(C)C)c2O)C(=O)C1=O)c3oc(C)cc3
InChIKey: RXIUEIPPLAFSDF-CYBMUJFWSA-N
Mol. Mass: 397.43
ALogP: 2.9 Partition coefficient
ChEMBL Molecules:

navarixin

navarixin

More Chemistry

Pharmacology

Mechanisms of Action:
- C-X-C chemokine receptor type 1 (Homo sapiens) ^UniProt
- C-X-C chemokine receptor type 2 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

2-hydroxy-n,n-dimethyl-3-(2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide | mk-7123 | navarixin | navarixin anhydrous | navarixin hydrate | ps-291822 | sch527123 | sch 527123 | sch-527123

Organizations (1)

Research & Development (1)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (7)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (7)

Asthma (Phase 2)

Carcinoma, Non-Small-Cell Lung (Phase 2)

Colorectal Neoplasms (Phase 2)

Neoplasms (Phase 2)

Prostatic Neoplasms, Castration-Resistant (Phase 2)

Psoriasis (Phase 2)

Pulmonary Disease, Chronic Obstructive (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 8
# of Trial Organizations: 1

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

Report issue