ro5126766 Report issue

Small molecule Experimental
AACT ChEMBL PubChem

Active Ingredient History

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Chemistry

  • SMILES: CNS(=O)(=O)Nc1nccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1F
  • InChIKey: LMMJFBMMJUMSJS-UHFFFAOYSA-N
  • Mol. Mass: 471.47
  • ALogP: 2.68
  • ChEMBL Molecules:
    avutometinib  
    rg-7304  
More Chemistry

Pharmacology

Alternative names

cki-27 | rg-7304 | ro5126766 | ro-5126766

Organizations (12)

Research & Development (12)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (17)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (17)


 

Brain Neoplasms (Phase 1)

Carcinoma, Endometrioid (Phase 1)

Carcinoma, Non-Small-Cell Lung (Phase 1/Phase 2)

Central Nervous System Neoplasms (Phase 1)

Glioblastoma (Early Phase 1)

Glioma (Phase 1)

Lung Neoplasms (Phase 1/Phase 2)

Multiple Myeloma (Phase 1)

Mutation (Phase 1/Phase 2)

Neoplasm Metastasis (Phase 1/Phase 2)

Neoplasms (Phase 1/Phase 2)

Neuroblastoma (Phase 1)

Neurofibroma (Phase 1)

Neurofibroma, Plexiform (Phase 1)

Ovarian Neoplasms (Phase 3)

Pancreatic Neoplasms (Phase 1)

Thyroid Neoplasms (Phase 2)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 10
  • # of Trial Organizations: 12

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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