Active Ingredient History

NOW
  • Now
Basmisanil is a highly selective inverse agonist/negative allosteric modulator of α5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome. As of June 2016, it is no longer studied. It is studied with schizophrenia patients.   Wikipedia

  • SMILES: Cc1onc(c1COc2ccc(cn2)C(=O)N3CCS(=O)(=O)CC3)c4ccc(F)cc4
  • InChIKey: VCGRFBXVSFAGGA-UHFFFAOYSA-N
  • Mol. Mass: 445.47
  • ALogP: 2.63
  • ChEMBL Molecule:
More Chemistry
basmisanil | rg1662 | rg-1662

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