Active Ingredient History
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is encoded by the IL10 gene. IL-10 signals through a receptor complex consisting of two IL-10 receptor-1 and two IL-10 receptor-2 proteins. Consequently, the functional receptor consists of four IL-10 receptor molecules. IL-10 binding induces STAT3 signalling via the phosphorylation of the cytoplasmic tails of IL-10 receptor 1 + IL-10 receptor 2 by JAK1 and Tyk2 respectively. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Bile Duct Diseases (Phase 2)
Biliary Tract Diseases (Phase 2)
Breast Neoplasms (Phase 1)
Carcinoma, Non-Small-Cell Lung (Phase 2)
Carcinoma, Renal Cell (Phase 1)
Cicatrix (Phase 2)
Colorectal Neoplasms (Phase 1)
Gallbladder Diseases (Phase 2)
Granulomatosis with Polyangiitis (Phase 1)
Healthy Volunteers (Phase 1)
Melanoma (Phase 1)
Neoplasms (Phase 1)
Ovarian Neoplasms (Phase 1)
Pancreatic Diseases (Phase 2)
Pancreatic Neoplasms (Phase 3)
Pancreatitis (Phase 2)
Prostatic Neoplasms (Phase 1)
Psoriasis (Phase 2)
Vasculitis (Phase 1)
Wound Healing (Phase 2)
| Trial | Phase | Start Date | Organizations | Indications |
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