palovarotene (Sohonos) Report issue

Small molecule Orphan Drug FDA Approved FDA Priority Review FDA

Active Ingredient History

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Palovarotene, sold under the brand name Sohonos, is a medication used for the treatment of heterotopic ossification and fibrodysplasia ossificans progressiva. It is a highly selective retinoic acid receptor gamma (RARγ) agonist. It is taken by mouth.   Wikipedia

  • SMILES: CC1(C)CCC(C)(C)c2cc(\C=C\c3ccc(cc3)C(=O)O)c(Cn4cccn4)cc12
  • InChIKey: YTFHCXIPDIHOIA-DHZHZOJOSA-N
  • Mol. Mass: 414.55
  • ALogP: 6.15
  • ChEMBL Molecule:
More Chemistry
clm-001 | palovarotene | r-667 | rar gamma | rar gamma1 | rar gamma2 | rar gamma3 | rar-gamma-a protein, mouse | rargb protein, zebrafish | rarg protein, human | rarg protein, mouse | retinoic acid receptor gamma | retinoic acid receptor gamma-1 protein, human | retinoic acid receptor, gamma, human | retinoic acid receptor, gamma, mouse | rg-667 | ro-3300074

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