ranpirnase (Onconase) Report issue

Animal product Experimental
AACT ChEMBL DrugBank MeSH

Active Ingredient History

NOW
  • Now
Ranpirnase is a ribonuclease enzyme found in the oocytes of the Northern Leopard Frog. Ranpirnase is a member of the pancreatic ribonuclease protein superfamily and degrades RNA substrates with a sequence preference for uracil and guanine nucleotides. Along with amphinase, another leopard frog ribonuclease, Ranpirnase has been studied as a potential cancer and antiviral treatment due to its unusual mechanism of cytotoxicity tested against transformed cells and antiviral activity.   Wikipedia

Chemistry

More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

onconase | p-30 protein | p-30 protein, rana pipiens | p30 protein, rana pipiens | pannon | ranpirnase

Organizations (2)

Research & Development (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (6)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (6)


 

Carcinoma, Non-Small-Cell Lung (Phase 2)

Condylomata Acuminata (Phase 1/Phase 2)

Conjunctivitis (Phase 2)

Mesothelioma, Malignant (Phase 3)

Papillomavirus Infections (Phase 1/Phase 2)

Sexually Transmitted Diseases (Phase 1/Phase 2)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 4
  • # of Trial Organizations: 2

Trials by Phase

Trial Phase Start Date Organizations Indications

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