Active Ingredient History
Calcium salicylate is the calcium salt of salicylic acid. The anti-cancer effectiveness of calcium salicylate has been investigated on human HT-1080 fibrosarcoma cell lines. Low calcium salicylate concentrations did not retard tumor growth progression significantly but its cytotoxic characteristics were proven to be prominent by various morphological and immunocytological techniques - approximately 25% apoptosis after treatment with calcium salicylate. This compound up-regulated the expression of p53, p21 and Bax, and down-regulated Bcl-2 in HT-1080 cells. In addition, calcium salicylate is used in root canal filling material development. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Arthritis (approved 2008)
Back Pain (approved 2008)
Contusions (approved 2008)
Ichthyosis Vulgaris (approved 2012)
Keratoderma, Palmoplantar (approved 2012)
Psoriasis (approved 2012)
Sprains and Strains (approved 2008)
Acne Vulgaris (Phase 4)
Contusions (Phase 3)
Dermatitis, Atopic (Phase 4)
Dermatitis, Seborrheic (Phase 4)
Healthy Volunteers (Phase 1/Phase 2)
Insulin Resistance (Phase 2/Phase 3)
Keratosis (Phase 2)
Keratosis, Actinic (Phase 3)
Leukemia (Phase 1)
Melanosis (Phase 4)
Myalgia (Phase 3)
Myelodysplastic Syndromes (Phase 1)
Myeloproliferative Disorders (Phase 1)
Pain (Phase 3)
Platelet-Rich Plasma (Phase 3)
Poisoning (Phase 2)
Psoriasis (Phase 3)
Quality of Life (Phase 4)
Skin Diseases (Phase 4)
Sprains and Strains (Phase 3)
Stroke (Phase 3)
Tendinopathy (Phase 3)
Warts (Phase 4)
Trial | Phase | Start Date | Organizations | Indications |
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