Active Ingredient History

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Calcium salicylate is the calcium salt of salicylic acid. The anti-cancer effectiveness of calcium salicylate has been investigated on human HT-1080 fibrosarcoma cell lines. Low calcium salicylate concentrations did not retard tumor growth progression significantly but its cytotoxic characteristics were proven to be prominent by various morphological and immunocytological techniques - approximately 25% apoptosis after treatment with calcium salicylate. This compound up-regulated the expression of p53, p21 and Bax, and down-regulated Bcl-2 in HT-1080 cells. In addition, calcium salicylate is used in root canal filling material development.   NCATS

  • SMILES: [Ca++].OC1=C(C=CC=C1)C([O-])=O.OC2=C(C=CC=C2)C([O-])=O
  • InChIKey: VBIGULIJWJPALH-UHFFFAOYSA-L
  • Mol. Mass: 314.304
  • ALogP: 1.09
  • ChEMBL Molecule:
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Drug Pricing (per unit)

United States

$0.1856 - $26.7780
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

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