Active Ingredient History

NOW
  • Now
Colchicine is an alkaloid obtained from the plant colchicum autumnale (also known as "meadow saffron"). Colchicine is an alternative medication for those unable to tolerate NSAIDs in gout. Mechanism of action of colchicine is inhibition of microtubule polymerization by binding to tubulin. Availability of tubulin is essential to mitosis, so colchicine effectively unctions as a "mitotic poison" or spindle poison.   NCATS
Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort
  • Highest Phase: Phase 4
  • # of Trials: 141
  • # of Trial Organizations: 140

  • SMILES: COC1=CC2=C(C(OC)=C1OC)C3=CC=C(OC)C(=O)C=C3[C@H](CC2)NC(C)=O
  • InChIKey: IAKHMKGGTNLKSZ-INIZCTEOSA-N
  • Mol. Weight: 399.437
  • ALogP: 2.87
More Chemistry
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Drug Pricing (per unit)

Australia

$0.1062 - $0.1778

United States

$0.1686 - $31.5333
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( procaine benzylpenicillin (novocaine), colchicine (colbenemid) - other names: col-probeneci, proben-c )
colchicin | colchicina | colchicine | colchicinum | colchisol | colcin | colcrys

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