tandospirone Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

NOW
  • Now
Tandospirone, sold under the brand name Sediel, is an anxiolytic and antidepressant medication used in Japan and China, where it is marketed by Dainippon Sumitomo Pharma. It is a member of the azapirone class of drugs and is closely related to other azapirones like buspirone and gepirone.   Wikipedia

Chemistry

  • SMILES: O=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1CCCCN1CCN(c2ncccn2)CC1
  • InChIKey: CEIJFEGBUDEYSX-FZDBZEDMSA-N
  • Mol. Mass: 383.5
  • ALogP: 1.41
  • ChEMBL Molecules:
    tandospirone  
    tandospirone citrate  
More Chemistry

Pharmacology

Alternative names

3a,4,7,7a-hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-4,7-methano-1h-isoindole-1,3(2h)-dione | 4,7-methano-1h-isoindole-1,3(2h)-dione, hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, (3aalpha,4beta,7beta,7aalpha)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) | al-8309b | metanopirone citrate | sm 3997 | sm-3997 | tandospirone | tandospirone citrate

Organizations (7)

Research & Development (7)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (8)

Approved Indications (1)


 

Anxiety

Experimental Indications - Clinical Trial Phases 1-4 (8)


 

Alzheimer Disease (Phase 4)

Anxiety (Phase 4)

Anxiety Disorders (Phase 4)

Cognition (Phase 4)

Geographic Atrophy (Phase 3)

Hypertension (Phase 4)

Macular Degeneration (Phase 3)

Schizophrenia (Phase 4)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 5
  • # of Trial Organizations: 7

Trials by Phase

Trial Phase Start Date Organizations Indications

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