piperine Report issue

Small molecule Experimental
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

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Piperine, possibly along with its isomer chavicine, is the compound responsible for the pungency of black pepper and long pepper. It has been used in some forms of traditional medicine.   Wikipedia

Chemistry

  • SMILES: O=C(\C=C\C=C\c1ccc2OCOc2c1)N3CCCCC3
  • InChIKey: MXXWOMGUGJBKIW-YPCIICBESA-N
  • Mol. Mass: 285.34
  • ALogP: 3.0
  • ChEMBL Molecule:
    piperine  
More Chemistry

Pharmacology

Alternative names

((1-5-(1,3)-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)piperidine | (1-(5-(1,3)-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)piperidine | 1-piperoylpiperidine | bioperine | bioprine | piperine | piperine, (e,e)-isomer | piperine, (e,z)-isomer | piperine, (z,e)-isomer | piperine, (z,z)-isomer

Organizations (17)

Research & Development (17)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (16)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (16)


 

Aging (Phase 1/Phase 2)

Clonal Hematopoiesis (Phase 2)

Deglutition Disorders (Phase 1/Phase 2)

Monoclonal Gammopathy of Undetermined Significance (Phase 2)

Multiple Myeloma (Phase 2)

Myelodysplastic Syndromes (Phase 2)

Neoplasms (Phase 1)

Obesity (Phase 1/Phase 2)

Pain (Phase 1)

Polycythemia Vera (Phase 2)

Primary Myelofibrosis (Phase 2)

Prostatic Neoplasms (Phase 2)

Renal Insufficiency, Chronic (Phase 3)

Thrombocythemia, Essential (Phase 2)

Urinary Bladder Diseases (Phase 1)

Urination Disorders (Phase 1)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 16
  • # of Trial Organizations: 17

Trials by Phase

Trial Phase Start Date Organizations Indications

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