Active Ingredient History

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Picosulfuric acid (as sodium picosulfate) is a contact laxative, which is used in combination with: magnesium oxide, and anhydrous citric acid for cleansing of the colon as a preparation for colonoscopy in adults. Sodium picosulfate is a prodrug. It has no significant direct physiological effect on the intestine. But it is hydrolyzed by colonic bacteria to form an active metabolite: bis-(p-hydroxy-phenyl)-pyridyl-2-methane, BHPM, which acts directly on the colonic mucosa to stimulate colonic peristalsis   NCATS

  • SMILES: OS(=O)(=O)Oc1ccc(cc1)C(c2ccc(OS(=O)(=O)O)cc2)c3ccccn3
  • InChIKey: UJIDKYTZIQTXPM-UHFFFAOYSA-N
  • Mol. Mass: 437.45
  • ALogP: 2.63
  • ChEMBL Molecules:
More Chemistry
  • Mechanisms of Action: Missing data
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Oral
  • Pro Drug: No

Combination drugs

( magnesium oxide, sodium picosulfate, citric acid - other name: clenpiq )
4,4'-(2-picolylidene)bisphenylsulfuric acid | 4,4'-(picoliliden)-bis-phenylsulphate | citrafleet | da-1773 | dulcolax pico | la-391 | laxoberal | natrium picosulfate | otc concepts | picolax | picoprep | picosalax | pico-salax | picosulfate | picosulfate sodium | picosulfol | picosulfuric acid | picosulphate | prepopik | rapilax | sodium picosulfate | sodium picosulfate, magnesium oxide and citric acid | sodium picosulphate

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