mitapivat (Pyrukynd) Report issue

Small molecule Orphan Drug FDA Approved FDA First in Class Fast Track FDA Priority Review FDA
AACT

Active Ingredient History

NOW
  • Now

Chemistry

  • SMILES: O.O.O.O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCN(CC2CC2)CC1.O=C(c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1)N1CCN(CC2CC2)CC1.O=S(=O)(O)O
  • InChIKey: DMRIPASJCJRBMV-UHFFFAOYSA-N
  • Mol. Mass: 1053.25
  • ALogP: 3.2
  • ChEMBL Molecules:
    mitapivat sulfate  
    mitapivat  
More Chemistry

Pharmacology

Alternative names

ag-348

Organizations (6)

Research & Development (5)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (2)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (11)

Approved Indications (2)


 

Anemia, Hemolytic (approved 2022)

Anemia, Hemolytic, Congenital

Experimental Indications - Clinical Trial Phases 1-4 (10)


 

alpha-Thalassemia (Phase 3)

Anemia (Phase 3)

Anemia, Hemolytic (Phase 4)

Anemia, Sickle Cell (Phase 2/Phase 3)

Asian People (Phase 1)

beta-Thalassemia (Phase 3)

Deficiency Diseases (Phase 4)

Healthy Volunteers (Phase 1)

Liver Diseases (Phase 1)

Thalassemia (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 24
  • # of Trial Organizations: 5

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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