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Small molecule Experimental

AACT ChEMBL PubChem

Active Ingredient History

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Chemistry

SMILES: CN1CCC(c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)C1CO
InChIKey: QLUYMIVVAYRECT-UHFFFAOYSA-N
Mol. Mass: 401.85
ALogP: 3.3 Partition coefficient
ChEMBL Molecule:
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More Chemistry

Pharmacology

Mechanisms of Action:
- Cyclin-dependent kinase 1 (Homo sapiens) ^UniProt
- Cyclin-dependent kinase 4 (Homo sapiens) ^UniProt
- Cyclin-dependent kinase 9 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

p276-00 | riviciclib

Organizations (37)

Research & Development (37)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (7)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (7)

Breast Neoplasms (Phase 1)

Lymphoma, Mantle-Cell (Phase 2)

Melanoma (Phase 2)

Multiple Myeloma (Phase 1/Phase 2)

Neoplasms (Phase 1)

Pancreatic Neoplasms (Phase 1/Phase 2)

Squamous Cell Carcinoma of Head and Neck (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 11
# of Trial Organizations: 37

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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