Active Ingredient History

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Oxazepam is the first of a chemical series of compounds, the 3-hydroxybenzodiazepinones. A therapeutic agent providing versatility and flexibility in control of common emotional disturbances, this product exerts prompt action in a wide variety of disorders associated with anxiety, tension, agitation and irritability, and anxiety associated with depression. Oxazepam has distinguished itself clinically from other benzodiazepines by virtue of its excellent tolerance. Because of its excellent tolerance, dosage is very flexible, and it is, therefore, possible to utilize oxazepam in a wide spectrum of anxiety-related disorders including the psychoses. Oxazepam has been administered to humans by the oral route only. Usual ranges for kinetic parameters are: elimination half-life, 5 to 15 hours; volume of distribution, 0.6 to 2.0 L/kg; clearance, 0.9 to 2.0 ml/min/kg. Age and liver disease have a minimal influence on oxazepam kinetics, but renal disease is associated with a prolonged half-life and increased volume of distribution.   NCATS

  • SMILES: OC1N=C(C2=CC=CC=C2)C3=CC(Cl)=CC=C3NC1=O
  • InChIKey: ADIMAYPTOBDMTL-UHFFFAOYSA-N
  • Mol. Mass: 286.713
  • ALogP: 2.45
  • ChEMBL Molecule:
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Drug Pricing (per unit)

Australia

$0.0375 - $0.1058

United States

$0.8123 - $1.4833
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

droxacepam | durazepam | lederpam | noctazepam | oxazepam | (+-)-oxazepam | oxozepam | (rs)-oxazepam | serax | serenid fte | tazepam | wy-3498 | zaxopam

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