Active Ingredient History

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Terbinafine (brand name Lamisil, Terbisil, Terboderm and others) is an antifungal medication used to treat ringworm and fungal nail infections. Terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents the conversion of squalene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis. Many side effects and adverse drug reactions have been reported with oral terbinafine hydrochloride possibly due to its extensive biodistribution and the often extended durations involved in antifungal treatment (longer than two months).   NCATS

More Chemistry
  • Mechanisms of Action: Missing data
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Over the Counter
  • Delivery Methods: Oral, Topical
  • Pro Drug: No

Drug Pricing (per unit)

Australia

$0.3491 - $11.4124
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

athlete's foot | da 5505 | (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalene methanamine | (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethylamine | (e)-n-(6,6-dimethyl-2-heptenynyl)-n-methyl-1-naphthalenementhamin hydrochloride | lamisil | lamisil at | lamisil once | sf 86-327 | sf-86327 | sf-86-327 | tdt-067 | terbinafina | terbinafine | terbinafine hcl | terbinafine hydrochloride | terbinafine, (z)-isomer | terbinafinum | terbinol

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