otilonium bromide (Spasmomen) Report issue

Small molecule Experimental
AACT ChEMBL Drug Central MeSH PubChem

Active Ingredient History

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Otilonium bromide, sold under the trade name Spasmomen among others, is an antimuscarinic and calcium channel blocker used to relieve spasmodic pain of the gut, especially in irritable bowel syndrome. This means it works in the gut themselves, by relaxing the small muscles of the intestines, which results in relieving cramps and therefore reduces pain.   Wikipedia

Chemistry

  • SMILES: [Br-].CCCCCCCCOc1ccccc1C(=O)Nc2ccc(cc2)C(=O)OCC[N+](C)(CC)CC
  • InChIKey: VWZPIJGXYWHBOW-UHFFFAOYSA-N
  • Mol. Mass: 563.58
  • ALogP: 6.32
  • ChEMBL Molecule:
    otilonium bromide  
More Chemistry

Pharmacology

Alternative names

n-diethylmethylammoniummethyl-p-(2-(n-octyloxy)benzoyl)aminobenzoate bromide | octylonium | octylonium bromide | octylonium iodide | otilonium bromide | sp63 | spasmomen

Organizations (3)

Research & Development (3)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (3)

Approved Indications (1)


 

Irritable Bowel Syndrome

Experimental Indications - Clinical Trial Phases 1-4 (3)


 

Gastroscopy (Phase 4)

Irritable Bowel Syndrome (Phase 4)

Spasm ()

Overview

  • Highest Phase: Phase 4
  • # of Trials: 3
  • # of Trial Organizations: 3

Trials by Phase

Trial Phase Start Date Organizations Indications

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