Active Ingredient History

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Nitroprusside is a medication which is used to lower blood pressure. It is comprised of a ferrous ion complexed with five cyanide and one nitrosyl group. Upon intravenous infusion, nitroprusside interacts with oxyhemoglobin and dissociates, releasing cyanide and nitric oxide, which act as a powerful vasodilating agent. Sodium nitroprusside was approved by the FDA in 1974 and is indicated for the immediate reduction of blood pressure of adult and pediatric patients in hypertensive crises. Sodium Nitroprusside injection is also indicated for producing controlled hypotension in order to reduce bleeding during surgery, and for the treatment of acute congestive heart failure.   NCATS

More Chemistry
  • Mechanisms of Action: Missing data
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Parenteral
  • Pro Drug: No
[fe(cn)5(no)](2-) | nipride | nitroferricyanide | nitropress | nitroprussiat | nitroprussiate | nitroprusside | nitroprusside sodium | nitroprusside sodium salt | sodium nitroferricyanide | sodium nitroprussiate | sodium nitroprusside | sodium nitroprusside hydrate | sodium nitrosylpentacyanoferrate

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