Active Ingredient History
Budesonide is a glucocorticoid used in the management of asthma, the treatment of various skin disorders, allergic rhinitis and ulcerative colitis. The precise mechanism of corticosteroid actions on inflammation in asthma is not well known. Inflammation is an important component in the pathogenesis of asthma. Corticosteroids have been shown to have a wide range of inhibitory activities against multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in allergic- and non-allergic-mediated inflammation. The anti-inflammatory actions of corticosteroids may contribute to their efficacy in asthma. Commonly reported side effects of budesonide include: acne vulgaris, moon face, and bruise. Other side effects include: ankle edema, hirsutism, weakness, arthralgia, nausea, and rhinitis. Ketoconazole, a potent inhibitor of cytochrome P450 (CYP) isoenzyme 3A4 (CYP3A4), the main metabolic enzyme for corticosteroids, increased plasma levels of orally ingested budesonide. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
Combination drugs
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Asthma (approved 2000)
Colitis, Ulcerative (approved 2013)
Crohn Disease (approved 2001)
Rhinitis, Allergic, Perennial (approved 2015)
Acute Chest Syndrome (Phase 1)
Acute Lung Injury (Phase 4)
Aged (Phase 4)
Air Pollution (Phase 4)
Airway Management (Phase 4)
Altitude Sickness (Phase 3)
Anemia, Sickle Cell (Phase 1)
Anosmia (Phase 3)
Arthroplasty, Replacement, Hip (Phase 3)
Aspergillosis, Allergic Bronchopulmonary (Phase 2/Phase 3)
Asthma (Phase 4)
Asthma, Exercise-Induced (Phase 4)
Autoimmune Diseases (Phase 4)
Breast Neoplasms (Phase 3)
Bronchiectasis (Phase 4)
Bronchiolitis Obliterans (Phase 2)
Bronchitis (Phase 4)
Bronchoalveolar Lavage Fluid (Phase 4)
Bronchopulmonary Dysplasia (Phase 4)
Budesonide (Phase 4)
Celiac Disease (Phase 4)
Cholangitis, Sclerosing (Phase 1)
Colitis (Phase 3)
Colitis, Collagenous (Phase 3)
Colitis, Lymphocytic (Phase 3)
Colitis, Microscopic (Phase 3)
Colitis, Ulcerative (Phase 4)
Collagenous Sprue (Phase 4)
Conjunctivitis, Allergic (Phase 3)
Coronavirus Infections (Phase 4)
COVID-19 (Phase 3)
Crohn Disease (Phase 4)
Cryptogenic Organizing Pneumonia (Phase 2)
Cytokines (Phase 4)
Diabetes Mellitus (Phase 2)
Diarrhea (Phase 2/Phase 3)
Emphysema (Phase 3)
Environmental Exposure (Phase 4)
Eosinophilic Esophagitis (Phase 4)
Esophageal Stenosis (Phase 2)
Estradiol (Phase 2/Phase 3)
Exercise (Phase 4)
Fasting (Phase 1)
Gastritis (Phase 3)
Gastroesophageal Reflux (Phase 2/Phase 3)
Gastroparesis (Phase 1)
General Surgery (Phase 4)
Genetic Diseases, Inborn (Phase 4)
Glomerulonephritis, IGA (Phase 2)
Glucocorticoids (Phase 4)
Graft Rejection (Phase 4)
Graft vs Host Disease (Phase 3)
Healthy Volunteers (Phase 4)
Hematopoietic Stem Cell Transplantation (Phase 2)
Hepatitis, Autoimmune (Phase 2/Phase 3)
Hypersensitivity (Phase 2/Phase 3)
Hypoxia (Phase 3)
Infant, Extremely Premature (Phase 4)
Infant, Premature (Phase 4)
Infant, Premature, Diseases (Phase 4)
Infections (Phase 2/Phase 3)
Inflammation (Phase 4)
Inflammatory Bowel Diseases (Phase 2)
Intestinal Diseases (Phase 4)
Intestinal Neoplasms (Phase 2)
Intestinal Polyposis (Phase 3)
Intubation (Phase 1/Phase 2)
Kidney Diseases (Phase 3)
Leukemia (Phase 3)
Leukemia, Lymphoid (Phase 4)
Ligaments, Articular (Phase 1)
Liver Cirrhosis, Biliary (Phase 3)
Liver Transplantation (Phase 4)
Lung Diseases (Phase 4)
Lung Diseases, Interstitial (Phase 2)
Lung Diseases, Obstructive (Phase 2)
Lung Neoplasms (Phase 4)
Malaria, Vivax (Phase 1)
Medication Adherence (Phase 4)
Melanoma (Phase 2)
Mouth Breathing (Phase 3)
Multiple Myeloma (Phase 2)
Multiple Sclerosis, Relapsing-Remitting (Phase 1)
Nasal Polyps (Phase 4)
Neonatology (Phase 3)
Neoplasm Metastasis (Phase 2)
Olfaction Disorders (Phase 3)
Olfactory Nerve Diseases (Phase 4)
Osteoporosis (Phase 4)
Paranasal Sinus Diseases (Phase 2/Phase 3)
Pharmacokinetics (Phase 1)
Pharyngitis (Phase 2/Phase 3)
Pneumonia (Phase 3)
Precancerous Conditions (Phase 1)
Proctitis (Phase 3)
Proctocolitis (Phase 3)
Protein-Losing Enteropathies (Phase 4)
Pulmonary Disease, Chronic Obstructive (Phase 4)
Quality of Life (Phase 4)
Radiation Pneumonitis (Phase 2)
Respiratory Distress Syndrome (Phase 4)
Respiratory Sounds (Phase 1)
Respiratory Syncytial Virus Infections (Phase 1)
Respiratory Tract Infections (Phase 2)
Rhinitis (Phase 4)
Rhinitis, Allergic (Phase 4)
Rhinitis, Allergic, Perennial (Phase 4)
Rhinitis, Allergic, Seasonal (Phase 3)
SARS-CoV-2 (Phase 3)
Severe Acute Malnutrition (Phase 2)
Sinusitis (Phase 4)
Sleep Apnea, Obstructive (Phase 4)
Sleep Disorders, Intrinsic (Phase 3)
Snoring (Phase 3)
Status Asthmaticus (Phase 2/Phase 3)
Stem Cell Transplantation (Phase 1)
Therapeutic Equivalency (Phase 1)
Transient Tachypnea of the Newborn (Phase 2)
Vascular Grafting (Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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