arfolitixorin Report issue

Small molecule Experimental
AACT ChEMBL DrugBank PubChem

Active Ingredient History

NOW
  • Now
5,10-Methylenetetrahydrofolate (N5,N10-Methylenetetrahydrofolate; 5,10-CH2-THF) is cofactor in several biochemical reactions. It exists in nature as the diastereoisomer [6R]-5,10-methylene-THF.   Wikipedia

Chemistry

  • SMILES: NC1=NC(=O)C2=C(NCC3CN(CN23)c4ccc(cc4)C(=O)N[C@@H](CCC(=O)O)C(=O)O)N1
  • InChIKey: QYNUQALWYRSVHF-ABLWVSNPSA-N
  • Mol. Mass: 457.45
  • ALogP: -0.52
  • ChEMBL Molecule:
    folitixorin  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

6r-mthf | folitixorin | modufolin

Organizations (4)

Research & Development (4)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (2)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (2)


 

Colorectal Neoplasms (Phase 3)

Healthy Volunteers (Phase 1)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 4
  • # of Trial Organizations: 4

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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