API | acolbifene

acolbifene Report issue

Small molecule Experimental

AACT ChEMBL PubChem

Active Ingredient History

NOW

Acolbifene is a nonsteroidal selective estrogen receptor modulator (SERM) which, as of 2015, is in phase III clinical trials for the treatment of breast cancer. ^Wikipedia

Chemistry

SMILES: CC1=C(c2ccc(O)cc2)[C@H](c2ccc(OCCN3CCCCC3)cc2)Oc2cc(O)ccc21.Cl
InChIKey: BYQDPIXWTVEVEA-JMAPEOGHSA-N
Mol. Mass: 494.03
ALogP: 6.03 Partition coefficient
ChEMBL Molecule:
acolbifene hydrochloride

More Chemistry

Pharmacology

Mechanism of Action:
- Estrogen receptor (Homo sapiens) ^UniProt
- Estrogen receptor beta (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

acolbifene | acolbifene hcl | acolbifene hydrochloride | sch-57068 hcl

Organizations (2)

Research & Development (2)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (1)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (1)

Breast Neoplasms (Phase 2)

Overview

Highest Phase: Phase 2
# of Trials: 1
# of Trial Organizations: 2

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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