Active Ingredient History

NOW
  • Now
Aclidinium is a long-acting, competitive, and reversible anticholinergic drug that is specific for the acetylcholine muscarinic receptors. It binds to all 5 muscarinic receptor subtypes to a similar affinity. It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012. Aclidinium's effects on the airways are mediated through the M3 receptor at the smooth muscle to cause bronchodilation. Prevention of acetylcholine-induced bronchoconstriction effects was dose-dependent and lasted longer than 24 hours.   NCATS

  • SMILES: OC(C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c4cccs4)c5cccs5
  • InChIKey: ASMXXROZKSBQIH-VITNCHFBSA-N
  • Mol. Mass: 484.66
  • ALogP: 4.67
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Prescription Only
  • Delivery Methods: Topical
  • Pro Drug: No

Drug Pricing (per unit)

Australia

$37.4702

United States

$135.6600 - $274.3400
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

14115700 | (3r)-3-((hydroxy(di-2-thienyl)acetyl)oxy)-1-(3-phenoxypropyl)-1-azoniabicyclo(2.2.2)octane bromide | aclidininum bromide | aclidinium | aclidinium bromide | aclidinium bromide / formoterol fumarate dihydrate | aclidinium bromide, micronised | aclidinium / formoterol fumarate dihydrate | eklira | las 34273 | las-34273 | las-34273 micronized | las w-330 | tudorza pressair

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