Active Ingredient History
Lipid A is a lipid component of an endotoxin held responsible for the toxicity of gram-negative bacteria. It is the innermost of the three regions of the lipopolysaccharide (LPS), also called endotoxin molecule, and its hydrophobic nature allows it to anchor the LPS to the outer membrane. While its toxic effects can be damaging, the sensing of lipid A by the immune system may also be critical for the onset of immune responses to gram-negative infection, and for the subsequent successful fight against the infection. Wikipedia
Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Hepatitis B (Phase 3)
Herpes Labialis (Phase 3)
Herpes Simplex (Phase 3)
HIV (Phase 1)
HIV Infections (Phase 1)
Hypersensitivity, Immediate (Phase 1)
Leishmaniasis (Phase 1)
Leishmaniasis, Cutaneous (Phase 2)
Lung Neoplasms (Phase 1/Phase 2)
Melanoma (Phase 1/Phase 2)
Neoplasms (Phase 1/Phase 2)
Norovirus (Phase 1)
Ovarian Neoplasms (Phase 1/Phase 2)
Trial | Phase | Start Date | Organizations | Indications |
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