Laromustine (onrigin) Report issue

Small molecule Experimental
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW
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Chemistry

  • SMILES: CNC(=O)N(N(CCCl)S(C)(=O)=O)S(C)(=O)=O
  • InChIKey: PVCULFYROUOVGJ-UHFFFAOYSA-N
  • Mol. Mass: 307.78
  • ALogP: -1.0
  • ChEMBL Molecule:
    laromustine  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: Yes

Alternative names

101m | 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-((2-methylamino)carbonyl)hydrazine | cloretazine | laromustine | onrigin | vnp40101m | vnp 40101m | vnp-40101m

Organizations (8)

Research & Development (8)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (10)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (10)


 

Brain Neoplasms (Phase 1)

Hematologic Neoplasms (Phase 1)

Intestinal Neoplasms (Phase 1)

Leukemia (Phase 3)

Leukemia, Myeloid, Acute (Phase 1/Phase 2)

Lung Neoplasms (Phase 2)

Lymphoma (Phase 1/Phase 2)

Myelodysplastic Syndromes (Phase 2)

Myeloproliferative Disorders (Phase 2)

Neoplasms (Phase 1)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 15
  • # of Trial Organizations: 8

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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