acadesine (arasine) Report issue

Small molecule Experimental
AACT ChEMBL DrugBank Drug Central KEGG MeSH PubChem

Active Ingredient History

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Chemistry

  • SMILES: NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1N
  • InChIKey: RTRQQBHATOEIAF-UUOKFMHZSA-N
  • Mol. Mass: 258.23
  • ALogP: -2.82
  • ChEMBL Molecule:
    acadesine  
More Chemistry

Pharmacology

Alternative names

1-(5'-phosphoribosyl)-5-amino-4-imidazolecarboxamide | 1-ribosyl-4-carboxamido-5-aminoimidazole | 4-carboxy-5-aminoimidazole ribotide | 5-amino-1-(5-phospho-d-ribosyl)imidazole-4-carboxamide | 5-amino-1-beta-d-ribofuranosyl-4-imidazolecarboxamide | 5-amino-1-beta-d-ribofuranosylimidazole-4-carboxamide monophosphate | 5-amino-4-imidazolecarboxamide ribofuranoside 5'-monophosphate | 5-aminoimidazole-4-carboxamide 1-ribofuranoside | 5-aminoimidazole-4-carboxamide riboside | 5-aminoimidazole-4-carboxamide ribotide | 5-phosphoribosyl-4-carbamoyl-5-aminoimidazole | 5'-phospho-ribosyl-5-amino-4-imidazole carboxamide | 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide | acadesine | acadesine 5'-monophosphate | aicar | aica ribofuranoside | aica ribonucleoside | aica ribonucleotide | aica-ribonucleotide | aica ribonucleotide, (d-ribofuranosyl)-isomer | aica riboside | aica-riboside | aicariboside 5'-monophosphate | aminoimidazole carboxamide ribonucleoside | aminoimidazole carboxamide ribonucleotide | ara100 | ara 100 | ara-100 | arasine | cair | gp 1 110 | gp-1-110 | zmp | z-nucleotide | z-riboside

Organizations (9)

Research & Development (9)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (8)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (8)


 

Bacterial Infections ()

Cardiopulmonary Bypass (Phase 3)

Coronary Artery Bypass (Phase 3)

Leukemia, Lymphocytic, Chronic, B-Cell (Phase 1/Phase 2)

Macular Degeneration (Phase 1/Phase 2)

Myocardial Infarction (Phase 3)

Stroke (Phase 3)

Ventricular Dysfunction, Left (Phase 3)

Overview

  • Highest Phase: Phase 3
  • # of Trials: 4
  • # of Trial Organizations: 9

Trials by Phase

Trial Phase Start Date Organizations Indications

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