Active Ingredient History

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  • Now
Ipratropium (ipratropium bromide, ATROVENT® HFA) is a muscarinic antagonist structurally related to atropine but often considered safer and more effective for inhalation use. It is indicated for the maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Ipratropium (ipratropium bromide, ATROVENT® HFA) is an anticholinergic (parasympatholytic) agent which, based on animal studies, appears to inhibit vagally-mediated reflexes by antagonizing the action of acetylcholine, the transmitter agent released at the neuromuscular junctions in the lung. Anticholinergics prevent the increases in intracellular concentration of Ca2+ which is caused by interaction of acetylcholine with the muscarinic receptors on bronchial smooth muscle.   NCATS

  • SMILES: CC(C)[N+]1(C)[C@@H]2CC[C@H]1C[C@H](C2)OC(=O)C(CO)c3ccccc3
  • InChIKey: OEXHQOGQTVQTAT-BHIXFJMTSA-N
  • Mol. Mass: 332.46
  • ALogP: 2.85
  • ChEMBL Molecules:
More Chemistry
  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: Yes
  • Availability: Prescription Only
  • Delivery Methods: Topical
  • Pro Drug: No

Drug Pricing (per unit)

United States

$0.0983 - $19.4200

Australia

$6.2954 - $16.7000
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Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Combination drugs

( ipratropium (atrovent), albuterol (proventil) - other names: combivent respimat, duoneb )
3α-hydroxy-8-isopropyl-1αh,5αh-tropanium bromide (±)-tropate | 8-isopropylnoratropine methobromide | albuterol sulfate mixture with ipratropium bromide | atrovent | atrovent aerocaps | atrovent fte | atrovent hfa | atrovent udvs | bromure d'ipratropium | bromuro de ipratropio | (endo,syn)-(±)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane bromide | ipratrop | ipratropii bromidum | ipratropium | ipratropiumbromid | ipratropium bromide | ipratropium bromide anhydrous | ipratropium bromide (anhydrous) | ipratropium bromide hydrate | ipratropium bromide monohydrate | ipratroprium | ipratrop steripoule | n-isopropylnoratropinium bromomethylate | respontin | rinatec | sch-1000-br- | sch-1000-br monohydrate | tropiovent

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