ephedrine Report issue

Small molecule Approved FDA
AACT ChEMBL DrugBank Drug Central Drugs@FDA KEGG MeSH PubChem repoDB

Active Ingredient History

NOW
  • Now
Ephedrine (l-form) is an alkaloid, which was initially purified from Ephedra plant. The extract form Ephedra has been used in China for medicinal purposes for several thousand years. Ephedrine acts as an agonist at alpha- and beta-adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. The drug crosses the blood brain barrier and stimulates the central nervous system. Ephedrine products are now banned in many countries, as they are a major source for the production of the addictive compound methamphetamine. FDA has approved ephedrine only for the treatment of clinically important hypotension occurring in the setting of anesthesia.   NCATS

Chemistry

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Pharmacology

Drug Pricing (per unit)

United States

$8.0388 - $23.1156
More Pricing Detail

Note: This drug pricing data is preliminary, incomplete, and may contain errors.

Alternative names

(1r,2s)-1-phenyl-1-hydroxy-2-methylaminopropane | amesec | aminophyline - amobarbital - pseudophedrine | aminophyline, amobarbital, pseudophedrine drug combination | asmapax | bronchipax | c.a.m. | chlorpheniramine - ephedrine | chlorpheniramine, ephedrine drug combination | demazin chronosules | do-do | ephed hcl | ephed in nor saline | ephedra | ephedrin | ephedrine | (-)-ephedrine | ephedrine hcl | ephedrine hydrochloride | ephedrine - phenobarbital - theophylline | ephedrine, phenobarbital, theophylline drug combination | ephedrine sulfate | ephedrine sulphate | ephetonin | expansyl | expurhin | franol | franol plus | franol-plus | haymine | isofedrol | l-ephedrine | l(-)-ephedrine | l-erythro-2-(methylamino)-1-phenylpropan-1-ol | novafed a syrup | sch-4855 | secron | tabasan | taumasthman | tedral | tedralan | tedral sa

Organizations (100)

Research & Development (72)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (28)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (33)

Approved Indications (3)


 

Asthma

Hypotension (approved 2016)

Obesity

Experimental Indications - Clinical Trial Phases 1-4 (32)


 

Anesthesia (Phase 4)

Anesthesia, Epidural (Phase 4)

Anesthesia, General (Phase 4)

Anesthesia, Intravenous (Phase 4)

Anesthesia, Spinal (Phase 4)

Blood Coagulation (Phase 2)

Bradycardia (Phase 4)

Brain Neoplasms (Phase 4)

Cardiac Output, Low (Phase 4)

Cesarean Section (Phase 4)

Cognition Disorders (Phase 2/Phase 3)

Dexmedetomidine (Phase 4)

Ephedrine (Phase 4)

Extracorporeal Membrane Oxygenation (Phase 4)

Gallstones (Phase 4)

General Surgery (Phase 4)

Hemodynamics (Phase 4)

HIV Infections (Phase 2)

Hypotension (Phase 4)

Infant, Newborn (Phase 2)

Injections, Intramuscular (Phase 4)

Labor, Obstetric (Phase 4)

Labor Pain (Phase 4)

Myasthenic Syndromes, Congenital (Phase 1/Phase 2)

Nausea (Phase 2)

Obesity ()

Pain (Phase 1/Phase 2)

Pre-Eclampsia (Phase 4)

Pregnancy (Phase 4)

Rapid Sequence Induction and Intubation (Phase 3)

Rhinitis, Allergic, Perennial (Phase 3)

Vomiting (Phase 2)

Overview

  • Highest Phase: Phase 4
  • # of Trials: 72
  • # of Trial Organizations: 72

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

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