Active Ingredient History
Human platelet lysate is a substitute supplement for fetal bovine serum (FBS) in experimental and clinical cell culture. It is a turbid, light-yellow liquid that is obtained from human blood platelets after freeze/thaw cycle(s). The freeze/thaw cycle causes the platelets to lyse, releasing a large quantity of growth factors necessary for cell expansion. hPL has the highest concentration of growth factors of any serum suppliments. FBS-free cell culture media, e.g. with platelet lysate or chemically defined/ animal component free, are used for cell therapy or regenerative medicine. They are commercially available in GMP -quality which is generally basis for regulatory approval. Wikipedia
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
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Achilles Tendon (Phase 4)
Acne Vulgaris (Phase 3)
Adrenal Cortex Hormones (Early Phase 1)
Airway Extubation (Phase 1/Phase 2)
Alopecia (Phase 4)
Alopecia Areata (Phase 4)
Alveolar Bone Loss (Phase 2/Phase 3)
Amenorrhea (Phase 2/Phase 3)
Anosmia (Phase 2/Phase 3)
Anterior Cruciate Ligament Injuries (Phase 4)
Arthritis (Phase 4)
Arthritis, Rheumatoid (Phase 1)
Arthroplasty (Early Phase 1)
Athletic Injuries (Phase 1)
Atrophic Vaginitis (Phase 1)
Back Injuries (Phase 4)
Back Pain (Phase 4)
Blood Platelets (Phase 4)
Bone Resorption (Phase 1)
Breast Neoplasms (Phase 4)
Bruxism (Phase 2/Phase 3)
Bursitis (Early Phase 1)
Carpal Tunnel Syndrome (Phase 3)
Cartilage Diseases (Phase 4)
Cesarean Section (Phase 2)
Chronic Disease (Phase 2)
Chronic Limb-Threatening Ischemia (Phase 1/Phase 2)
Chronic Pain (Phase 4)
Cicatrix, Hypertrophic (Phase 2)
Cleft Lip (Phase 2)
Colitis, Ulcerative (Phase 1)
Congenital Microtia (Early Phase 1)
Corneal Diseases (Phase 4)
Corneal Ulcer (Phase 4)
COVID-19 (Phase 2/Phase 3)
Cystitis, Interstitial (Phase 1/Phase 2)
Dental Implantation (Phase 3)
Dermatology (Phase 1/Phase 2)
Diabetes Complications (Phase 1)
Diabetes, Gestational (Phase 2/Phase 3)
Diabetes Mellitus (Phase 2/Phase 3)
Diabetes Mellitus, Type 1 (Phase 1/Phase 2)
Diabetes Mellitus, Type 2 (Phase 1)
Diabetic Foot (Phase 3)
Diabetic Retinopathy (Phase 2)
Dry Eye Syndromes (Phase 4)
Elbow (Phase 4)
Elbow Tendinopathy (Phase 4)
Endometrial Neoplasms (Phase 2)
Endometrium (Phase 2)
Endoscopic Mucosal Resection (Phase 3)
Erectile Dysfunction (Phase 2/Phase 3)
Facial Injuries (Phase 3)
Fasciitis, Plantar (Phase 4)
Fat Body (Phase 2/Phase 3)
Fecal Incontinence (Early Phase 1)
Female (Phase 2)
Femoracetabular Impingement (Phase 4)
Fertilization in Vitro (Phase 3)
Fissure in Ano (Phase 4)
Foot Ulcer (Phase 1)
Genital Diseases, Male (Phase 2)
Graft vs Host Disease (Phase 2)
Gynatresia (Phase 2)
Headache (Phase 1)
Hearing Loss (Phase 2/Phase 3)
Hearing Loss, Sensorineural (Phase 2/Phase 3)
Hearing Loss, Sudden (Phase 2/Phase 3)
Hyaluronic Acid (Phase 4)
Infant, Premature (Phase 1)
Infections (Phase 4)
Infertility (Phase 4)
Infertility, Female (Phase 2/Phase 3)
Intervertebral Disc Degeneration (Phase 3)
Joint Diseases (Phase 2)
Knee Injuries (Phase 4)
Leg Ulcer (Phase 1)
Lichen Planus (Phase 2)
Lipids (Phase 2/Phase 3)
Losartan (Phase 4)
Low Back Pain (Phase 4)
Melanosis (Phase 3)
Meniscus (Phase 4)
Menopause (Phase 2/Phase 3)
Menopause, Premature (Phase 2/Phase 3)
Menstrual Cycle (Phase 2/Phase 3)
Muscles (Phase 3)
Myalgia (Phase 2/Phase 3)
Neck Pain (Phase 2/Phase 3)
Neuralgia (Phase 1)
Osteoarthritis (Phase 4)
Osteoarthritis, Hip (Phase 3)
Osteoarthritis, Knee (Phase 4)
Otitis Media (Phase 2/Phase 3)
Ovarian Diseases (Phase 2/Phase 3)
Ovulation (Phase 2/Phase 3)
Pain (Phase 4)
Pain, Postoperative (Phase 4)
Pelvic Floor Disorders (Phase 2/Phase 3)
Pemphigus (Phase 3)
Penile Induration (Phase 2)
Peptic Ulcer (Phase 1/Phase 2)
Peripheral Arterial Disease (Phase 1/Phase 2)
Platelet-Rich Plasma (Phase 4)
Pneumothorax (Phase 1/Phase 2)
Popliteal Cyst (Phase 3)
Positron-Emission Tomography (Phase 1)
Postmenopause (Phase 1)
Pregnancy Outcome (Phase 2)
Primary Ovarian Insufficiency (Phase 2/Phase 3)
Rectal Fistula (Phase 4)
Respiratory Distress Syndrome (Phase 1/Phase 2)
Rhytidoplasty (Early Phase 1)
Rotator Cuff (Phase 2)
Rotator Cuff Injuries (Phase 4)
Sacroiliitis (Phase 4)
Sexual Dysfunction, Physiological (Phase 2)
Shoulder Injuries (Phase 3)
Shoulder Pain (Phase 4)
Sjogren's Syndrome (Phase 3)
Skin Aging (Phase 1/Phase 2)
Spinal Cord Injuries (Phase 1)
Sports Medicine (Phase 4)
Sprains and Strains (Phase 4)
Stromal Vascular Fraction (Phase 1)
Temporomandibular Joint Disorders (Phase 4)
Tendinopathy (Phase 4)
Tennis Elbow (Phase 3)
Therapeutics (Phase 4)
Tissue Adhesions (Phase 2)
Tooth Abnormalities (Phase 4)
Tooth Loss (Phase 2/Phase 3)
Traumatology (Phase 1)
Tympanic Membrane Perforation (Phase 2/Phase 3)
Ulcer (Phase 3)
Ultrasonography (Phase 4)
Urinary Incontinence (Phase 2/Phase 3)
Urinary Incontinence, Stress (Phase 2/Phase 3)
Vaginitis (Phase 1)
Varicose Ulcer (Phase 3)
Vision, Ocular (Phase 1/Phase 2)
Vulvar Lichen Sclerosus (Phase 2)
Warts (Phase 4)
Wound Healing (Phase 2)
Wounds and Injuries (Phase 2/Phase 3)
| Trial | Phase | Start Date | Organizations | Indications |
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