incyclinide Report issue

Small molecule Experimental
AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW
  • Now
Incyclinide is a chemically modified tetracycline antibiotic that was investigated in clinical trials for the treatment of rosacea, various tumours, allergic and inflammatory diseases and a number of other conditions.   Wikipedia

Chemistry

  • SMILES: NC(=O)C1=C(O)C[C@@H]2C[C@@H]3Cc4cccc(O)c4C(=O)C3=C(O)[C@]2(O)C1=O
  • InChIKey: ZXFCRFYULUUSDW-OWXODZSWSA-N
  • Mol. Mass: 371.35
  • ALogP: 0.58
  • ChEMBL Molecule:
    incyclinide  
More Chemistry

Pharmacology

  • Mechanism of Action:
  • Multi-specific: Missing data
  • Black Box: No
  • Availability: Missing data
  • Delivery Methods: Missing data
  • Pro Drug: No

Alternative names

4-dedimethylaminosancycline | 4-dedimethylamino sancycline | 6-col-3 cpd | 6-demethyl-6-deoxy-4-dedimethylaminotetracycline | 6-demethyl-6-deoxy-4-dedimethylamino-tetracycline | 6-deoxy-6-demethyl-4-dedimethylaminotetracycline | cmt-3 | col-3 | col-3 compound | incyclinide | metastat | tetracycline cmt-3

Organizations (4)

Research & Development (4)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Marketing (0)

Organization Org Type FDA approvals Clinical Trials involvement Org ID Force Sort

Indications (8)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (8)


 

Brain Neoplasms (Phase 1/Phase 2)

Carcinoma, Renal Cell (Phase 1)

HIV Infections (Phase 2)

Lymphoma (Phase 1)

Melanoma (Phase 1)

Neoplasm Metastasis (Phase 1)

Neoplasms (Phase 1)

Sarcoma, Kaposi (Phase 2)

Overview

  • Highest Phase: Phase 2
  • # of Trials: 4
  • # of Trial Organizations: 4

Trials by Phase

Trial Phase Start Date Organizations Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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