Active Ingredient History
Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. Nepafenac is manufactured by Alcon and sold under the trade name Nevanac. It is used to treat pain and inflammation associated with cataract surgery. After penetrating the cornea, nepafenac undergoes rapid bioactivation to amfenac, which is a potent NSAID that uniformly inhibits the COX1 and COX2 activity. NCATS
Drug Pricing (per unit)
Note: This drug pricing data is preliminary, incomplete, and may contain errors.
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
| Organization | Org Type | FDA approvals | Clinical Trials involvement | Org ID | Force Sort |
|---|
Cataract (approved 2005)
Cataract (Phase 4)
Conjunctivitis, Bacterial (Phase 2)
Corneal Endothelial Cell Loss (Phase 2)
Diabetic Retinopathy (Phase 3)
Endothelium (Phase 4)
Epiretinal Membrane (Phase 4)
General Surgery (Phase 4)
Hyperopia (Phase 4)
Inflammation ()
Intraocular Pressure (Phase 4)
Macula Lutea (Phase 2)
Macular Degeneration (Phase 4)
Macular Edema (Phase 4)
Miosis (Phase 2)
Myopia (Phase 4)
Pain (Phase 4)
Photorefractive Keratectomy (Phase 4)
Pseudophakia (Phase 4)
Retinal Vein Occlusion (Phase 4)
Uveitis (Phase 4)
Vitrectomy (Phase 4)
| Trial | Phase | Start Date | Organizations | Indications |
|---|
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