API | varespladib methyl ester

varespladib methyl ester Report issue

Small molecule Experimental

AACT ChEMBL DrugBank MeSH PubChem

Active Ingredient History

NOW

A-001 was the second abort test of the Apollo spacecraft. ^Wikipedia

Chemistry

SMILES: CCc1c(C(=O)C(=O)N)c2c(OCC(=O)O)cccc2n1Cc3ccccc3
InChIKey: BHLXTPHDSZUFHR-UHFFFAOYSA-N
Mol. Mass: 380.4
ALogP: 2.38 Partition coefficient
ChEMBL Molecules:

varespladib

varespladib methyl

More Chemistry

Pharmacology

Mechanisms of Action:
- Group 10 secretory phospholipase A2 (Homo sapiens) ^UniProt
- Phospholipase A2, membrane associated (Homo sapiens) ^UniProt
- Calcium-dependent phospholipase A2 (Homo sapiens) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

((3-(aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1h-indol-4-yl)oxy)acetate | a-001 | a-002 | ly315920 | ly 315920 | ly-315920 | ly333013 | ly-333013 | s-3013 | s 5920 | s-5920 | varepladib | varespladib | varespladib methyl | varespladib methyl ester | varespladib sodium

Organizations (4)

Research & Development (4)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (11)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (11)

Acute Chest Syndrome (Phase 2)

Acute Coronary Syndrome (Phase 3)

Anemia, Sickle Cell (Phase 2)

Arterial Occlusive Diseases (Phase 2)

Coronary Artery Disease (Phase 2)

COVID-19 (Phase 2)

Healthy Volunteers (Phase 1)

Kidney Failure, Chronic (Phase 1)

Severe Acute Respiratory Syndrome (Phase 2)

Snake Bites (Phase 2)

Venoms (Phase 2)

Overview

Highest Phase: Phase 3
# of Trials: 12
# of Trial Organizations: 4

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

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