API | iclaprim

iclaprim Report issue

Small molecule Experimental

AACT ChEMBL Drug Central KEGG MeSH PubChem

Active Ingredient History

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Chemistry

SMILES: COc1cc(Cc2cnc(N)nc2N)c3C=CC(Oc3c1OC)C4CC4
InChIKey: HWJPWWYTGBZDEG-UHFFFAOYSA-N
Mol. Mass: 354.41
ALogP: 2.43 Partition coefficient
ChEMBL Molecules:

iclaprim

iclaprim mesylate

More Chemistry

Pharmacology

Mechanism of Action:
- Dihydrofolate reductase type 1 (Escherichia coli) ^UniProt
Multi-specific: Missing data
Black Box: No
Availability: Missing data
Delivery Methods: Missing data
Pro Drug: No

ar 100 | ar-100 | iclaprim | iclaprim mesilate | iclaprim mesylate | ro-482622

Organizations (3)

Research & Development (3)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Marketing (0)

Organization	Org Type	FDA approvals	Clinical Trials involvement	Org ID	Force Sort

Indications (6)

Approved Indications (0)

Experimental Indications - Clinical Trial Phases 1-4 (6)

Bacterial Infections ()

Healthcare-Associated Pneumonia (Phase 2)

Infections (Phase 3)

Pneumonia, Ventilator-Associated (Phase 2)

Skin Diseases, Bacterial (Phase 3)

Soft Tissue Infections (Phase 3)

Overview

Highest Phase: Phase 3
# of Trials: 5
# of Trial Organizations: 3

Trials by Phase

Trial	Phase	Start Date	Organizations	Indications

Feedback

Data collection and curation is an ongoing process for CDEK - if you notice any information here to be missing or incorrect, please let us know! When possible, please include a source URL (we verify all data prior to inclusion).

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